Sunday 8 March 2015

Maggot Therapy

Also called; Biodebridement, Maggot debridement therapy (MDT) or Larval therapy.

This is the controlled, therapeutic application of live blowfly (Lucilia sp) larvae ("maggots") into non-healing wounds to to aid in wound debridement (cleaning), disinfection and/or healing.It can also be termed "Therapeutic Myiasis" as we recall that maggot infestation on a living vertebrate host is called "myiasis".
Maggot Therapy (Picture Credit; Science Open)

"Despite our low cultural esteem for maggots, more and more clinicians and patients are turning to medicinal maggots for assistance with their wound healing. For most, the drawbacks of maggot therapy pale in comparison to the remarkable efficacy in treating even the most recalcitrant wounds"- Ronald A. Sherman,

Though It sounds medieval, Maggot therapy is an accepted part of modern medicine as Debridement is an essential component of wound care; the presence of devitalized tissue can impede the healing process.

History Of Maggot Therapy
The beneficial effects of therapeutic myiasis were first observed during the Napoleonic war by Larrey, who noted that soldiers whose wounds had become infested with maggots had an improved prognosis.
William Baer, while at Johns Hopkins University in Baltimore, Maryland, may have been the first person to have intentionally applied larvae to wounds in order to induce wound healing. During the late 1920's, he identified certain species, raised them in the laboratory, and used their larvae to treat several children with osteomyelitis and soft tissue infections. He presented his findings at a surgical conference in 1929. Two years later, after treating 98 children, his findings were published posthumously.
Throughout the 1930’s Maggot Therapy was performed routinely by Doctors until the discovery of new antibiotics and surgical techniques that came out during World War II. Maggot therapy was occasionally used during the 1970's and 1980's, but only when antibiotics, surgery, and modern wound care failed to control the advancing wound.

The emergence of antibiotic-resistant strains of bacteria such as methicillin resistant Staphylococcus aureus (MRSA) and the curiosity of researchers prompted the reemergence of larval therapy during 1970's & 1980's . As a treatment it meets the demands of clinical governance, being not only beneficial to the patient, but also being proven to be more cost-effective.

In January 2004, the U.S. Food and Drug Administration (FDA) granted permission to produce and market Medicinal maggots. Same year the British National Health Service (NHS) gave approval for maggot therapy. Presently, about 30 countries around the world are using Maggot therapy; In Africa, it is being used in Kenya & South Africa. In European Union, Canada, Japan, maggots are classified as medicinal drugs, needing a full market license.

Mechanism Of Action
Debridement; The maggots secrete a broad spectrum of digestive juice (collagenases, proteolytic enzymes, serine proteases) that selectively liquefy and absorb only necrotic tissue (extracorporeal digestion). Also Mechanical Debridement by the specific mandibles or “mouth hooks” of the maggots and their rough body which both scratch the necrotic tissue.

Disinfection; It was discovered that secretions from maggots (allantoin, urea, phenylacetic acid, phenylacetaldehyde, calcium carbonate, proteolytic enzymes, etc) have broad-spectrum antimicrobial activity, and microbes not killed by these secretions are subsequently ingested and lysed within the maggots. Maggot secretions have been found to dissolve biofilms.

Stimulation of healing; The alkalinity of maggot-treated wounds, along with the isolated allantoin and urea-containing compounds is responsible for wound healing. In fact, today, allantoin and urea are components of many cosmetics. Maggot secretions also;
 -stimulates the proliferation of fibroblasts and endothelial tissue ,
 -increases angiogenesis,
 -enhances fibroblast migration over model wound surfaces.
Using remittance spectroscopy to evaluate patients before and after maggot therapy, Wollina and colleagues found that vascular perfusion and tissue oxygenation surrounding the wound actually increased following maggot therapy. Zhang and colleagues are currently seeing evidence that maggot extracts may even stimulate the growth of neural tissue.

Uses/Indication
  • Diabetic Foot Ulcer
  • For debriding non-healing necrotic skin and soft tissue wounds including;
               -pressure ulcers,
               -venous stasis ulcers,
               -neuropathic foot ulcers,
               -non-healing traumatic or post-surgical wounds
               -infectious
  • In diabetic and non-diabetic subjects for wound bed preparation prior to surgical closure.

Dosage & Administration
Maggots are applied to the wound at a dose of 5–10 larvae per square centimeter of wound surface area and are left within their dressing for 48–72 hrs. At that point they are satiated (as evidenced by increase in size), finished working, and can be removed and safely disposed.

Maggot therapy being a controlled therapeutic myiasis (maggot infestation on a live host) is controlled by;
selecting a safe and effective species and strain,
  • chemical disinfection to make the maggots germ-free (sterile maggots),
  • containing the maggots within special dressings(e.g maggot confinement dressings; Le Flap™,Biobag™ ) that prevent them from leaving the wound unescorted,
  • quality control measures throughout the breeding and production processes.
Not all species are safe and effective. The maggots cleared for marketing in the United States belong to the (currently named) LB-01 strain of Phaenicia (Lucilia) sericata.

Advantages Of Maggot Therapy
  1. Takes about 15-30 minutes to apply a secure dressing to keep the maggots in place
  2. Low cost of treatment
  3. Excellent safety record.
  4. Simple enough that non-surgeons can use it to provide thorough debridement when surgery is not available or is not the optimal choice
  5. Provide surgical quality debridement as an outpatient or in the home
  6. Provides treatment for wounds infected by strains of methicillin resistant Staphylococcus aureus (MRSA)
  7. As larvae are typically applied for 3 days, wounds are disturbed less frequently than conventional dressings that require changing everyday
Disadvantages
  1. Bacteria like Pseudomonas aeruginosa, Escherichia coli, Enterococcus, Proteus are not attacked by maggots and in case of Pseudomonas even the maggots are in danger. Consequently, using maggots alone might lead to a change of bacteria cultures on the wound.
  2. Ineffective in case of highly discharging or dried wounds
  3. Medicinal maggots are highly perishable and susceptible to transportation problems and delays. Young, starving larvae require food, water, and oxygen, and they are temperature sensitive. Therefore they must be shipped by overnight courier, and their arrival should be timed no more than 24 h before their application to the wound. Delivery delays and exposure to extreme temperatures decrease their survival.
  4. Occasionally the maggots may escape from the wounds and 1–2 weeks later become adult flies (“used maggots” and flies are essentially mobile fomites)
  5. Local discomfort, itching, unaesthetic appearance to the patient along with cost of the therapy and short half life of maggots
  6. It cannot be used in open wounds of body cavities as the environment is not suitable
  7. Negative perception with which it is regarded by both patients and doctors; The 'yuk factor'

Side Effects
Minor bleeding,Pain,
Excessively induced exudates,
Increased body temperature,
Flu-like symptoms,
Allergic reaction,
Skin maceration
Discomfort.

Contraindications
Patients refusal.

Alternative Therapies
  • Biotherapies like; apitherapy (application of honey) and application of leeches.
  • Sonotherapy (with use of ultrasounds)
  • Hydrosurgical therapy (with use of water jets)
  • Hyperbaric Oxygen Therapy (HBOT)
Medical Maggots™ (Picture Credit; Live science)


Maggot Debridement Therapy (Picture Credit; btmcl)


NOTES
1) A. J. Horobin, K. M. Shakesheff, S. Woodrow, C. Robinson, and D. I. Pritchard, “Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon interactions between human dermal fibroblasts and extracellular matrix components,” The British Journal of Dermatology, vol. 148, no. 5, pp. 422–933, 2003.

2) A. G. Smith, R. A. Powis, D. I. Pritchard, and S. T. Britland, “Greenbottle (Lucilia sericata) larval secretions delivered from a prototype hydrogel wound dressing accelerate the closure of model wounds,” Biotechnology Progress, vol. 22, no. 6, pp. 1690–1696, 2006.

3) Dariusz Waniczek, Andrzej Kozowicz, Maล‚gorzata Muc-Wierzgoล„, Teresa Kokot, Elลผbieta ลšwiฤ™tochowska, and Ewa Nowakowska-Zajdel, "Adjunct Methods of the Standard Diabetic Foot Ulceration Therapy,"  Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 243568 Chapter 3

4) P. E. Prete, “Growth effects of Phaenicia sericata larval extracts on fibroblasts: mechanism for wound healing by maggot therapy,” Life Sciences, vol. 60, no. 8, pp. 505–510, 1997.

5) R. A. Sherman, "Mechanisms of Maggot-Induced Wound Healing: What Do We Know, and Where Do We Go from Here?" Evidence-Based Complementary and Alternative Medicine
Volume 2014 (2014), Article ID 592419

6) R. A. Sherman, “Maggot therapy for foot and leg wounds,” International Journal of Lower Extremity Wounds, vol. 1, no. 2, pp. 135–142, 2002.


7) R. A. Sherman, "Maggot Therapy takes us back to the future of wound care: New and Improved Maggot Therapy for 21st Century" J Diabetes Sci Technol. 2009 Mar; 3(2): 336–344.

8) U. Wollina, K. Liebold, W. Schmidt, M. Hartmann, and D. Fassler, “Biosurgery supports granulation and debridement in chronic wounds—clinical data and remittance spectroscopy measurement,” International Journal of Dermatology, vol. 41, no. 10, pp. 635–639, 2002.

9) Wikipedia, "Maggot Therapy"

10) W. Robinson, “Stimulation of healing in non-healing wounds by allantoin occurring in maggot secretions and of wide biological distribution,” Journal of Bone and Joint Surgery, vol. 17, pp. 267–271, 1935

11) Z. Zhang, S. Wang, Y. Diao, J. Zhang, and D. Lv, “Fatty acid extracts from Lucilia sericata larvae promote murine cutaneous wound healing by angiogenic activity,” Lipids in Health and Disease, vol. 9, article 24, 2010.

12) Z. Zhang, S. Wang, X. Tian, Z. Zhao, J. Zhang, and D. Lv, “A new effective scaffold to facilitate peripheral nerve regeneration: chitosan tube coated with maggot homogenate product,” Medical Hypotheses, vol. 74, no. 1, pp. 12–14, 2010.

20 comments:

  1. Hello am Tanya Albert from United State, I was diagnose with genital HERPES since 2012 they where all spreading all over my body even on my private part two i have be taking lot treatment and all i got is outbreak. in 2015 I gave up the treatment because I can't continues wasting time and money on treatment at the end it will not cure me. about 2 Months ago i did natural research on line I had So many people talking good about natural remedy, after the research i was recommended to Dr Ekpiku, And I wrote to him through his email and told him my problem after some conversations with him he told me about his natural herbal treatment and he prepared me some herbs which i takes for some couples of days, and i take it as he says before i am to no i was perfectly cure of it and never experience it again. please friends if you have herpes virus and you really wants to get rid of it, please contact this great DR. Ekpiku for herbal treatment and you will get rid of it. EMAIL ekpikuspellhomeofgrace@gmail.com his whatapp contact is +2348073673757 thanks and GOD bless you all.

    ReplyDelete
    Replies
    1. Good day. I'm Mrs Lynn and I want to quickly share something with you. As of January 2019, I was having issues with my health and I was forced to go to the hospital. Only to be diagnosed of cancer. And as if that wasn't bad enough, it was prostate cancer. I felt like my greatest fear has finally caught up with me. I lived life like I wasn't existing no more. I was depressed, frustrated and most a times I contemplated suicide. Then one day while going through the internet checking for ways to get cured because I was getting sick of the too many drugs I was taking I stumbled across a post about a doctor called DR.Ehiaguna. I quickly messaged him because I was really desperate. I got a reply from DR.Ehiaguna and he told me what to do. And I did exactly as I was told and under two week I noticed changes. I could do things I normally found to be difficult and today I am cancer free and I will be forever grateful to doctor DR.Ehiaguna because he saved my life. Are you a cancer patient? Do you want to live a cancer free life? Then leave doctor Ehiaguna a message drehiaguna@gmail.com also WhatsApp him +2348073908953 and you'll be glad you did And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

      Delete
    2. AM RUFORS, FROM HOLAND, THANKS TO DR ONIHA WHO CURED ME FROM liver chirosis,FATTY LIVER PROBLEM and hepatitis b WITH HIS HERBAL MEDICATION. I WAS DIAGNOSED OF FATTY LIVER PROBLEEM FIVE YEARS AGO, I VISITED MEDICAL DIALYSIS CENTER, AND THERE WERE NO BETTER IMPROVEMENT, UNTIL I SAW DR ONIHA'S TESTIMONIES AND RECONMMENDATIONS ONLINE, ON HOW HE HAS BEEN CURING PEOPLE OF LIVER PROBLEMS, AND I DECIDED TO CONTACT HIM, AND HE ADMINISTERED HID DERBAL MEDICATION ON ME, WITHIN A MONTH, I WAS CURED. IN CASE YOU ARE PASSING THROUGH A SIMILAR PROBLEM AND YOU NEED DR ONIHA'S ASSISTANCE, YOU CAN CALL OR WHATSAP +2347089275769 OREMAIL: DRONIHASPELL@YAHOO.COM

      Delete
  2. Hello everyone, I want to thank Dr. Ogbeifun on how he saved my daughter’s life from XP. This story might seem strange to many of you but it’s real. My daughter was born with XP disease a rare genetic sickness, which means she had to wear PPE or risk skin cancer extremely easily. The only way she could avoid risking cancer is when the sun goes completely down---so basically at night and her night had to become day. Also when you open up the windows on a sunny day when you are inside, because the sun's rays even from the outside to the inside can still be very dangerous without protection. But despite all those she was still infected by the ultraviolent rays and doctors said she had few months to live. I couldn’t risk losing my daughter so I searched everywhere for a possible cure and browsed the internet till i came across a blog and read about a comment about a doctor from Africa Dr. Azeke and how he helped someone who had XP through his herbal medicine. I doubted at first but I had to give it a try so I contacted him, and told him about my daughter condition and what the doctors said about her, so he said he could help me and his herbal medicine would heal her and told me all I needed to do and sent me his medicine through DHL service. Upon 4 weeks of usage of his drugs, I took her for another test and the doctors was marveled and said she was clean and they found no trace of XP in her DNA. Am really grateful for what Dr. Ogbeifun, did for my daughter. You can also contact him yourself for whatever sickness you may have. email: ogbefunhearlingtemple@gmail.com website https://ogbefunhearlingtem.wixsite.com/spell call or add him on whatsapp +2348102574680

    ReplyDelete
  3. Hiv disease for the last 3 years and had pain hard to eat and cough are nightmares,especially the first year At this stage, the immune system is severely weakened, and the risk of contracting opportunistic infections is much greater. However, not everyone with HIV will go on to develop AIDS. The earlier you receive treatment, the better your outcome will be.I started taking ARV to avoid early death but I had faith in God that i would be healed someday.As a Hiv patent we are advise to be taking antiretroviral treatments to reduce our chance of transmitting the virus to others , few weeks ago i came on search on the internet if i could get any information on Hiv treatment with herbal medicine, on my search i saw a testimony of someone who has been healed from Hiv her name was Achima Abelard and other Herpes Virus patent Tasha Moore also giving testimony about this same man,Called Dr Itua Herbal Center.I was moved by the testimony and i contacted him by his Email.drituaherbalcenter@gmail.com We chatted and he send me a bottle of herbal medicine I drank it as he instructed me to.After drinking it he ask me to go for a test that how i ended my suffering life of Hiv patent,I'm cured and free of Arv Pills.I'm forever grateful to him Drituaherbalcenter.Here his contact Number +2348149277967...He assure me he can cure the following disease..Hiv,Cancer,Herpes Virus,Epilepsy, fibromyalgia ,ALS,Hepatitis,Copd,Parkinson disease.Diabetes,Fibroid...

    ReplyDelete
  4. Are you going through STAPHYLOCOCCUS? Doctor Uduehi is your best bet and I am a testimony to his great herbal cure. I suffered staphylococcus aureus for more than a year, and not too long ego I read about Dr. Uduehi’s recommendation online and after taking his medication all pains were gone. I ran 2 test and they both proof negative which means I am cured and free. Reach him through Email: uduehiherbalcare@gmail.com phone/WhatsaPP:+2347084878384

    ReplyDelete
  5. Don’t think of anything else just contact priest eka and purchase some of his herbal medication and your depression will go away. This was my state of mind when my doctor told me that i will not be able to concieve due to the Fibroid that was rolling in my family life and when i decide to reach out to the priest, and the priest told me what to do in other to get the medication. Eventually I receive all the Herbal medications that cure my Fibroid and give me the chance to become a proud mother: Eka is a great spiritualist, He did it for me, you can contact Eka on (dreka14demons@gmail.com). If you are suffering from the following gynecology disease::
    1. Fibroid, Hysterectomy, Asthma, All STD, sinus infection, unexplain miscarriage, fibromyalgia.
    2.High Blood Pressure (herbs to reduce your BP within 7days), Ucler
    3. Infection, regular body pains (yeast infection), urine tract infection. Thyroid infection, Skin infection Herbal cream
    4. Blockage from the fallopian Tube, Herbs to untied womb,Hepatitis
    5. Cyst from the ovaries, PCOS
    6. Unpleasant smell from the virginal, virginal itching, virginal discharge
    7. Irregular menstruation, painful period
    8. Weakness of the penis (not able to have sex with your partner or inability to satisfy your partner sexually)
    9. Watering sperm (low sperm count) not able to get woman pregnant. (Herbal cure for Weak Erection)
    10. Infertility for easy Conception.......
    11. Cure from all kinds of Skin diseases, Toilet infection and bad body odor…….Etc..
    Simply contact the spiritualist DrEka on (dreka14demons@gmail.com) to get his Herbal Medication to cure your disease and put yourself on a motherhood side of life..

    ReplyDelete
  6. I was diagnosed of HERPES in 2015, i have tried everything possible in life from one doctor to another, one hospital to another, series of tests different kinds of medication i had already lost hope until i meet Great DR OBUDU online testimonies, a specialist in herbal medication from Africa, i contacted him true his email OBUDU.MIRACLEHERBALHOME@GMAIL.COM and he prepared HERPES herbal medication for me which i took for 7days and now i am completely cured i want to use this medium to express my gratitude to him for saving my life and curing me from HERPES VIRUS for taking away all my pains and sorrows, I''m indeed grateful and i am so happy I''m now cured totally, I will continue to tell the good news of your great works to everyone, if you have HERPES or other disease contact him true his Email: OBUDU.MIRACLEHERBALHOME@GMAIL.COM Or whatsApp him via +2347035974895 thank you my great DR OBUDU for curing me keep up your great work

    ReplyDelete
  7. HOW DR AZIBA HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GROWTH
    I got married 2 years ago and it just seemed that there was no excitement in my sex life. My dysfunction to perform to the best of my abilities in bed made it harder for my wife and me to have a good time during sex. And i was having the feelings that she may decide to get a divorce one day. I knew something had to be done in order to improve my sex life and to save my marriage because my marriage was already falling apart, so when i was on my Facebook page i came across a story of how Dr Aziba helped him enlarged his penis to 8ins better.so i Immediately copied the Email address of the Dr and explained to him my problem,he gave me some simply instruction which i must follow and i did easily and my friends Today, i am the happiest man on Earth, All Thanks to Dr Aziba for saving my marriage and making me a real man today.i asked him about some popular diseases like HERPES,HIV AIDS,HEPATITIS, DIABETICS, CANCERS, WART, Get Ex back ,etc....... which are affecting most people he said there is no disease without a cure , he has it all...You can as well reach the Dr below for help on your problem, for he has the solution to all...
    Email:[ PRIESTAZIBASOLUTIONCENTER@GMAIL COM ]
    WhatsAPP DR [ +2348100368288 ]





    HOW DR AZIBA HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GROWTH
    I got married 2 years ago and it just seemed that there was no excitement in my sex life. My dysfunction to perform to the best of my abilities in bed made it harder for my wife and me to have a good time during sex. And i was having the feelings that she may decide to get a divorce one day. I knew something had to be done in order to improve my sex life and to save my marriage because my marriage was already falling apart, so when i was on my Facebook page i came across a story of how Dr Aziba helped him enlarged his penis to 8ins better.so i Immediately copied the Email address of the Dr and explained to him my problem,he gave me some simply instruction which i must follow and i did easily and my friends Today, i am the happiest man on Earth, All Thanks to Dr Aziba for saving my marriage and making me a real man today.i asked him about some popular diseases like HERPES,HIV AIDS,HEPATITIS, DIABETICS, CANCERS, WART, Get Ex back ,etc....... which are affecting most people he said there is no disease without a cure , he has it all...You can as well reach the Dr below for help on your problem, for he has the solution to all...
    Email:[ PRIESTAZIBASOLUTIONCENTER@GMAIL COM ]
    WhatsAPP DR [ +2348100368288 ]

    ReplyDelete
  8. i have been trying to get pregnant for over 5 years now. My husband and I have been seeing a fertility specialist. We have done our best but no luck. My husband has a sperm count which goes up and down,the doctor has recommended him taking the Proceed supplement which he is doing over 3 years with no change in the situation .. I was so confused until i contacted this powerful spell caster Dr. Osemuhau online who I saw a number of testimonies of how he has help so many of people so I sent Dr. Osemuhau a mail and I told him all my sorrows and pain he replied me and ask me not to cry any more that he will help, he sent me some instructions and caution, Dr. Osemuhau cast the spell and I bought some items to complete the spell casting and he told me to meet with my husband.. Within 3weeks of doing this I felt some changes and I went to my doctor and it was confirm that I was pregnant,i promises Dr Osemuhau to share his testimony for three years,it has been over a year and four months now,i have been testifying this great testimonies for my life and my husband,for any one how need his help herb potion should contact him,on his Email [ drosemuhau@gmail.com ] or call him on [ +2348168714427 ]

    ReplyDelete
  9. I want you all to help me thank Dr. OBUDU for saving my life, i was diagnosed of herpes and at the same time i was 7 months pregnant, i was confused and i didn't know what to do until i meant a friend on the Internet who directed me to Dr. OBUDU, i did not believe it until i contacted the good man who was able to help me out of the situation with his herbs, it only cost me some little amount of money to cure herpes through Dr. OBUDU so i will also advice any body that needs help from him should contact him because i know you will also get cured of your disease. Thanks once again Dr OBUDU. Anyone who needs help having the same disease should contact him on his email OBUDU.MIRACLEHERBALHOME@GMAIL.COM or call/whatsapp number +2347035974895

    ReplyDelete
  10. Dr. Iyabiye is a herbal specialist he treat/cure HEPATITIS and CIRRHOSIS and other deadly diseases. My name is Russel and I was ones a victim of chronic hepatitis B and liver cirrhosis, I got cured with his medication and I am safe and free now. I am testifying to his great work so that you too can be safe from hepatitis or any life threatening disease. His contacts are: iyabiyehealinghome@gmail.com Call/Whatsapp: +2348072229413

    ReplyDelete
  11. ARE YOU AWARE THAT MODERN NATURAL HERBAL MEDICINES OF THIS GENERATION NOW PERMANENTLY CURE DRUG RESISTANT DISEASES LIKE; HSV/HERPES, CANCERS, HIV/AIDS, ERECTILE DISJUNCTION/ IMPOTENCY, DIABETES FOREVER WITHOUT A POSSIBLE COME BACK OR AFTER EFFECTS?
    It wonderfully worked for me;
    At first I was a bit skeptical about this Natural cure for herpes and other similar medicines. Discovering people with similar symptoms who are treated and cured by Dr Utu both on medias and in social medias on daily basis motivated me, so I contacted him for help!
    At first, I was a bit curious about this possible cure, but! I don't want to be left out without giving it a trial, so I contacted him as well.
    Some hours later he replied me, then he asked me some private questions, of which I honestly answered, I told him how I have lived and suffered with this disease and how much I will do anything to get rid of it. He assured me of total cure after taking his herbal medicines. It was even more easier than I expected. Also I never even imagined to get my parcels within five working days, but to my greatest surprise my parcels was brought to my doorstep by the end of the second day. I collected the parcel which I followed all the instructions as he had directed. Just as I was told "four weeks medication " my medicine finished in four weeks exactly. From week one of my medication I started noticing positive change in health. and in week two I could tell much more differences and I was so eager to even testify of life again in me.
    I patiently continue medication till the last bottle which was then week four. I was the first person the next day in the clinic for lab test. Not even a particle of herpes was found in my system when I collected my result. Knowing I'm now herpes negative at this point I proceeded to inform my doctor, he doubted me, that day he gave me a month appointment to be closely monitored. It's my health so I waited more six Months and again i went for 'lab test' in a different clinical lab.
    This time the result was still the same as the previous one. Also since this year I have been living my normal life and am still herpes free no symptoms and even till now no cold sore or outbreak. As a result of this herbal cure in my life and my family at large, I can boast of doctors today who through me, now uses African Traditional Roots and Herbs to TREAT AND CURE patients that are, CANCERS, HERPES, PARALYSIS, and HIV successfully today. Many are still ignorant of this I know.
    Contact Dr Utu directly today on; "drutuherbalcure@gmail.com" to free yourself from emotional stress and become healthy again

    ReplyDelete
  12. Greetings to every one that is reading this testimony. I had been rejected by my husband after five(5) years of marriage just because another woman had cast a spell on him and he left me with 2 kids to suffer. One day when i was reading through the web, i saw a post on how he help a woman to get back her husband and i gave him a chance he told me that my husband is under spell, he said that he will help me and after 7 days that i will have my husband back. i believed he and today i am glad to let you all know that this spell caster has the power to bring lovers back now my husband is back with after 7 days . he also gave me a financial magic ring to boost my business and removed bad luck. i am now happy with my husband. Thanks you Dr. love please contact him at (lovespelldoctor0@gmail. com)

    ReplyDelete
  13. My name is hoover, my 18 years old daughter, Tricia was diagnosed of herpes 3 years ago. ever since then,we have been going from one hospital to the other. We tried all sorts of pills but all efforts to get rid of the virus was futile. The blisters kept on reappearing after some months. My daughter was making use of Acyclovir tablets 200mg. 2 tablets every 6hours and fusitin cream 15grams. and H5 POT. Permanganate with water to be applied 2x a day but all still show no result. So I was on the internet some months back, to sought for any other means of saving my only child. just then, i came across a comment on dr imoloa herbal treatment and decided to give it a try. i contacted the him and he prepared some herbs and sent it to me together with guidelines on how to use the herbs through DHL courier service. my daughter used it as directed dr imoloa and in less than 14days, my daughter regained her health.. You should contact Dr imoloa today directly on his email address for any kind of health challenge; lupus disease,  mouth ulcer,  mouth cancer, body pain, fever, hepatitis A.B.C.,   syphilis,  diarrhea,  HIV/AIDS,  Huntington's Disease,   back acne,  Chronic renal failure,   addison disease,  Chronic Pain,   Crohn's Disease,   Cystic Fibrosis,  Fibromyalgia,   Inflammatory Bowel Disease,  fungal nail disease, Lyme Disease, Celia disease, Lymphoma, Major Depression,  Malignant Melanoma,   Mania,  Melorheostosis,   Meniere's Disease,  Mucopolysaccharidosis , Multiple Sclerosis,  Muscular Dystrophy,  Rheumatoid Arthritis, Alzheimer's Disease, parkison disease, vaginal cancer, epilepsy,  Anxiety Disorders, Autoimmune Disease,   Back Pain,  Back Sprain,   Bipolar Disorder,  Brain Tumour,  Malignant,   Bruxism, Bulimia,  Cervical Disk Disease, cardiovascular disease, Neoplasms, chronic respiratory disease,  mental and behavioural disorder,     Cystic Fibrosis,   Hypertension, Diabetes, asthma,  Inflammatory autoimmune-mediated arthritis.  chronic kidney disease, inflammatory joint disease,  impotence,  feta alcohol spectrum,  Dysthymic Disorder,   Eczema, tuberculosis,  Chronic Fatigue Syndrome, constipation, inflammatory bowel disease.  and many more; contact him on email- drimolaherbalmademedicine@gmail.com./ also on  whatssap-+2347081986098.

    ReplyDelete
  14. I Want To Appreciate Dr.OYAGU for hs great deeds, I Was Diagnosed With type 2 Herpes Virus Last year,And Was Looking For Solution To Be Cured Luckily I Saw Testimonies On How Dr.OYAGU Cure Herpes Virus I Decided To Contact Dr.OYAGU I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me,I Started The Herbal Medicine For My Health.He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of This Deadly Herpes Within 2 weeks, I Am Now Herpes Negative.My Brother And Sister I No That There Are So Many People That Have There Same Herpes Virus Please contact Dr OYAGU To Help You Too,And Help Me To Thank Dr.OYAGU For Cure Me, I’m Cured By Dr. OYAGU Herbal Medicine,His Contact Email:oyaguherbalhome@gmail.com

    Or Cell Whatsapp Number +2348101755322 thank you

    ReplyDelete
  15. We all can help him share his great work so order people can see it plz OK., Dr Oyakhire has really made me so much believe in him by getting me cure with his herbal treatment. i really appreciate you Dr Oyakhire for bringing back happiness to my life again. thanks you so much friends that join me to thank Dr.Oyakhire for what he has actually done for me i pray to you all a good life and properity, email him at ...DrOyakhire7@gmail.com
    Whatsapp him +2349039208180
    He did cure those illness with herbal medicine!!!

    1 Cancer herbal medicine

    2 Hiv herbal medicine

    3 Low sperm count

    4 Barrenness

    5 Hvp herbal medicine

    6 Herpes herbal medicine

    7 Diabetes

    8 Love spell.

    9 Ex back

    Thanks Dr Oyakhire for your help in my life and family... and most especially to you Dr Oyakhire THANKS

    ReplyDelete
  16. Good day. I'm Mrs Lynn and I want to quickly share something with you. As of January 2019, I was having issues with my health and I was forced to go to the hospital. Only to be diagnosed of cancer. And as if that wasn't bad enough, it was prostate cancer. I felt like my greatest fear has finally caught up with me. I lived life like I wasn't existing no more. I was depressed, frustrated and most a times I contemplated suicide. Then one day while going through the internet checking for ways to get cured because I was getting sick of the too many drugs I was taking I stumbled across a post about a doctor called DR.Ehiaguna. I quickly messaged him because I was really desperate. I got a reply from DR.Ehiaguna and he told me what to do. And I did exactly as I was told and under two week I noticed changes. I could do things I normally found to be difficult and today I am cancer free and I will be forever grateful to doctor DR.Ehiaguna because he saved my life. Are you a cancer patient? Do you want to live a cancer free life? Then leave doctor Ehiaguna a message drehiaguna@gmail.com also WhatsApp him +2348073908953 and you'll be glad you did And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  17. Very informative, because it compresses most of the information needed and the best solution to Paralysis still remains herbal medicines.
    I became more convinced in herbal medicines because of NZE NJOKU HERBAL HOME.
    I have also contacted Nze Njoku for herbal treatment for my grandfather who had suffered paralysis caused by stroke for eight years.
    My grandfather took herbal medicines from Nze Njoku Herbal Home as he's instructed without any lifestyle change which healed him of paralysis within nine weeks.
    As I write this my grandfather is doing great on his feet and most importantly he has started his business effectively as if nothing happened to him.
    Feel free to contact them on;
    nzenjokuherbalhome@gmail.com

    ReplyDelete
  18. God bless Dr. Agbonhale for his marvelous work in my life, I was diagnosed of HERPES since 2018 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr. Agbonhale, how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine. I took the medicine as prescribed by him and 17 days later i was cured from HERPES you can reach him through his whatsapp +2349073130326 OR Email: dragbonhaleherbalhome@gmail.com

    ReplyDelete